The Pacific Northwest Tribal Wetlands Working Group (PNW TWIG) has supported development of Tribal wetland and aquatic resource programs since 2010. Efforts to establish similar groups in other parts of the country have not been successful with the exception of the Tribal Wisconsin Wetland Working Group (TWWWG) created in 2017. This paper explores the evolution of the PNW TWIG and the TWWWG, the benefits, lessons learned, and ongoing challenges in working group operation in an effort to gain insights into how it might be possible for Tribal Wetland Working Groups (TWWGs) to be established in EPA Region 5 and elsewhere across the U.S. Information was gathered through a series of interviews with Tribal wetland program staff in Oregon, Washington, Idaho, Minnesota, and Wisconsin as well as EPA staff in Regions 5, 10 and HQ (Appendix A).